南 蓬


职称:副教授

邮箱:nanpeng@fudan.edu.cn

研究方向:1.次生代谢产物活性成分筛选及其代谢途径的分子调控机制; 2.小分子化合物与靶蛋白的相互作用,药物不良反应及疾病基因突变分析。

个人简介

南蓬,博士,副教授

  1. 1987年  武汉大学化学系,获学士学位,

  2. 1987年-2000年  中科院武汉植物园,助理研究员/副研究员

  3. 2003年      中科院华南植物园,获植物学博士学位

  4. 2003年-2005年    复旦大学生科院,博士后

  5. 2005年-现在         复旦大学,副教授

代表性论文和专著

  1. Chen J, Wu XT, Xu YQ, Zhong Y, Li YX, Chen JK, Li X*, Nan P*. 2015. Global transcriptome analysis profiles metabolic pathways in traditional herb Astragalus membranaceus Bge. var. mongolicus (Bge.) Hsiao.  BMC Genomics.(已接收).

  2. Chen J, Yuan H, Zhang L, Pan HY, Xu RY, Zhong Y, Chen JK, Nan P*. 2015. Cloning, expression and purification of isoflavone-2’-hydroxylase from Astragalus membranaceus Bge. var. mongolicus (Bge.) Hsiao. Protein Expression and Purification, 107: 83-89.

  3. Chen J, Sheng J, Lv DJ,  ZhongY, Zhang GQ, Nan P*. 2014. The Optimization of Running Time for a Maximum Common Substructure-Based Algorithm and Its Application in Drug Design. Computational Biology and Chemistry, 48:14-20.

  4. Zhao JY, Zheng XX, Newman RA, Zhong Y, Liu ZJ, Nan P*. 2013. Chemical composition and bioactivity of the essential oil of Artemisia anomala from China. J Essent Oil Res, 25: 520-525.

  5. Xu R, Nan P, Yang YX, Pan HY, Zhou TS and Chen CK. 2011. Ultraviolet irradiation induces accumulation of isoflavonoids and transcription of genes of enzymes involved in the calycosin-7-O-β-D-glucoside pathway in Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao. Physiologia Plantarum, 142: 265-273. (并列第一)

  6. Wei WQ,Liu FQ, Liu L, Li ZF, Jiang F, Shi Q, Zhou XY, Sheng WQ,  Cai S,Li X, Xu Y, Nan P*. 2011. Distinct mutations in MLH1 and MSH2 genes in Hereditary Non-polyposis Colorectal Cancer (HNPCC) families from China. BMB Reports, 44: 317-322.

  7. Zhao JY, Liu JM, Zhang X, Liu Z, Tashi Tsering, Zhong Y and Nan P*. 2006. Chemical composition of the volatiles of three wild Bergenia species from western China. Flavour Fragr. J., 21: 431-434.

  8. Nan P, Shi S, Peng S, Tian C and Zhong Y. 2003.Genetic diversity of Primula obconica (Primulaceae) from central and southwest China as revealed by ISSR markers. Ann. Bot., 91: 329-333.

  9. Nan P, Peng S, Shi S, Ren H, Yang J and Zhong Y. 2003. Interpopulation congruence in Chinese Primula ovalifolia revealed by chemical and molecular markers using essential oils and ISSRs. Z. Naturforschung, 58c: 57-61.

主要课题

  1. 生态因子调控蒙古黄芪毛蕊异黄酮及其糖苷的分子机理,国家自然科学基金面上项目,主持

  2. 转基因渐渗对水稻野生近缘种的进化和生态影响机制研究,国家自然科学基金重点项目,参加,负责其中的转基因对水稻及其野生近缘种相关次生代谢的分子调控研究

  3. 医学知识库与临床决策支持系统研发,国家863项目,参加,负责其中中药物不良反应的研究